SCHEMBL23949933

SCHEMBL23949933

CC[C@H]1[C@@H](C)c2cccc(F)c2N[C@H]1c1ccc(C(=O)O)cc1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 4/20 0.43
▸ MAPT P10636 3/20 0.43
▸ GAA P10253 2/20 0.43
▸ LIN28A Q9H9Z2 1/20 0.43
▸ PSD A5PKW4 1/20 0.40
▸ TTR P02766 1/20 0.40
▸ MEN1 O00255 2/20 0.36
▸ KMT2A Q03164 2/20 0.36
▸ PTPN7 P35236 1/20 0.35
▸ PLA2G4B P0C869 4/20 0.34
▸ HNF4A P41235 1/20 0.33
▸ PDE5A O76074 1/20 0.32
▸ ALDH1A1 P00352 3/20 0.31
▸ KDM4E B2RXH2 1/20 0.31
▸ HPGD P15428 1/20 0.31
▸ RORC P51449 2/20 0.31
▸ PLA2G4A P47712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23949923 0.87 MAPT (0.44) POLBMAPTGAALIN28APSD
SCHEMBL23949930 0.82 MAPT (0.40) POLBMAPTGAALIN28APSD
SCHEMBL23949460 0.81 HNF4A (0.39) POLBMAPTGAALIN28APSD
SCHEMBL23949791 0.77 POLB (0.44) POLBMAPTGAALIN28APSD
SCHEMBL17704819 0.71 PSD (0.76) POLBMAPTGAALIN28APSD
SCHEMBL23949919 0.71 FPR1 (0.36) POLBMAPTGAALIN28AMEN1
SCHEMBL23949491 0.68 MEN1 (0.42) POLBMAPTGAAMEN1KMT2A
SCHEMBL23949921 0.68 NR4A1 (0.41) POLBMAPTGAAMEN1KMT2A
SCHEMBL23949932 0.67 PIN1 (0.37) MAPTALDH1A1HPGD
SCHEMBL23949908 0.64 DYRK2 (0.41) POLBMAPTGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021209689-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING SWEET POTATO AGAINST SWEET POTATO PATHOGENIC VIRUSES HELSINGIN YLIOPISTO (FI) 2021-10-21 — — WO disclosed
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