Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23950186 | 0.83 | NLRP3 (0.36) | NLRP3EPHX2 | |
| SCHEMBL23950194 | 0.81 | NLRP3 (0.37) | NLRP3EPHX2 | |
| SCHEMBL25293967 | 0.79 | NLRP3 (0.34) | NLRP3EPHX2 | |
| SCHEMBL23950971 | 0.78 | GAA (0.33) | NLRP3 | |
| SCHEMBL23950454 | 0.74 | NLRP3 (0.48) | NLRP3 | |
| SCHEMBL23950797 | 0.71 | TOP2A (0.38) | NLRP3 | |
| SCHEMBL23950172 | 0.70 | NLRP3 (0.60) | NLRP3 | |
| SCHEMBL25752450 | 0.70 | KDM4E (0.38) | NLRP3 | |
| SCHEMBL23950967 | 0.68 | CYP2C19 (0.35) | NLRP3 | |
| SCHEMBL25753005 | 0.66 | NLRP3 (0.51) | NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021209552-A1 | PYRAZOLO[1,5-D][1,2,4]TRIAZINE-5(4H)-ACETAMIDES AS INHIBITORS OF THE NLRP3 INFLAMMASOME PATHWAY | JANSSEN PHARMACEUTICA NV (BE) | 2021-10-21 | — | — | WO | disclosed |