Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23568674 | 0.83 | AR (0.41) | ARKDM1ASMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL23569535 | 0.83 | AR (0.41) | ARKDM1ASMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL23569538 | 0.82 | KDM1A (0.42) | ARKDM1AALDH1A1MAPTKDM4E | |
| SCHEMBL25457709 | 0.82 | KDM1A (0.42) | ARKDM1AALDH1A1MAPTKDM4E | |
| SCHEMBL227927 | 0.82 | AR (0.46) | ARKDM1ASMN1; SMN2PDE3BPDE3A | |
| SCHEMBL6249460 | 0.81 | SRD5A1 (0.44) | ARKDM1ASMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL23568679 | 0.81 | AR (0.42) | ARKDM1ASMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL25457710 | 0.78 | KDM1A (0.44) | ARKDM1AALDH1A1CYP3A4THRB | |
| SCHEMBL6252680 | 0.78 | AR (0.45) | ARKDM1ASMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL23569287 | 0.77 | NR3C1 (0.56) | ARKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787835-B2 | C19 scaffolds and steroids and methods of use and manufacture thereof | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2023-10-17 | — | — | US | disclosed |
| US-11787835-B2 | C19 scaffolds and steroids and methods of use and manufacture thereof | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2023-10-17 | — | — | US | disclosed |
| US-20230151053-A1 | METHODS FOR ASSEMBLY OF TETRACYCLIC COMPOUNDS BY STEREOSELECTIVE C9-C10 BOND FORMATION | TRUSTEES OF DARTMOUTH COLLEGE | 2023-05-18 | — | — | US | disclosed |
| US-20230151053-A1 | METHODS FOR ASSEMBLY OF TETRACYCLIC COMPOUNDS BY STEREOSELECTIVE C9-C10 BOND FORMATION | TRUSTEES OF DARTMOUTH COLLEGE | 2023-05-18 | — | — | US | disclosed |
| US-20210323998-A1 | C19 SCAFFOLDS AND STEROIDS AND METHODS OF USE AND MANUFACTURE THEREOF | TRUSTEES OF DARTMOUTH COLLEGE | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151053-A1 | METHODS FOR ASSEMBLY OF TETRACYCLIC COMPOUNDS BY STEREOSELECTIVE C9-C10 BOND FORMATION | C9, NDC1, RTCB | AR 3914/4885KDM1A 4086/4885SMN1; SMN2 380/4885 |
| US-20210323998-A1 | C19 SCAFFOLDS AND STEROIDS AND METHODS OF USE AND MANUFACTURE THEREOF | CYP17A1, HSD17B7, CYP11A1 | AR 487/4885KDM1A 4109/4885SMN1; SMN2 1102/4885 |
| US-11787835-B2 | C19 scaffolds and steroids and methods of use and manufacture thereof | CYP17A1, HSD17B7, CYP11A1 | AR 487/4885KDM1A 4109/4885SMN1; SMN2 1102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.