Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12017682 | 0.84 | CHRM3 (0.36) | PTPN1CHRM3CHRM2CHRM4CHRM5 | |
| SCHEMBL12786920 | 0.84 | PTPN1 (0.41) | PTPN1CHRM3CHRM2CHRM4CHRM5 | |
| SCHEMBL5906945 | 0.82 | PTPN1 (0.50) | PTPN1CHRM3CHRM2CHRM4CHRM5 | |
| SCHEMBL12326213 | 0.82 | LOXL2 (0.41) | PTPN1CHRM3CHRM2CHRM4CHRM5 | |
| SCHEMBL20373494 | 0.78 | PTPN1 (0.40) | PTPN1CHRM3CHRM2CHRM4CHRM5 | |
| SCHEMBL13673421 | 0.77 | GABRP (0.31) | LMNABLMTSHR | |
| SCHEMBL12905841 | 0.75 | PTPN1 (0.45) | PTPN1CHRM3CHRM2CHRM4CHRM5 | |
| SCHEMBL10036725 | 0.73 | PTPN1 (0.44) | PTPN1CHRM3CHRM2CHRM4CHRM5 | |
| SCHEMBL14614628 | 0.73 | PTPN1 (0.44) | PTPN1CHRM3CHRM2CHRM4CHRM5 | |
| SCHEMBL6858231 | 0.73 | PTPN1 (0.55) | PTPN1CHRM3CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4137483-A1 | BENZONITRIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Zhongze Therapeutics, Co. Ltd. (CN) | 2023-02-22 | — | — | EP | disclosed |
| WO-2021208945-A1 | BENZONITRIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海中泽医药科技有限公司 | 2021-10-21 | — | — | WO | disclosed |