Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dicloxacillin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 4/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.90 |
| ▸ | HPGD | P15428 | 3/20 | 0.84 |
| ▸ | LMNA | P02545 | 3/20 | 0.84 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.84 |
| ▸ | MEN1 | O00255 | 1/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.84 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.82 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.59 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dicloxacillin SCHEMBL8727180 | 1.00 | ABCB11 (1.00) | ABCB11CYP1A2HPGDLMNATDP1 | |
| Dicloxacillin SCHEMBL11407716 | 1.00 | ABCB11 (1.00) | ABCB11CYP1A2HPGDLMNATDP1 | |
| Dicloxacillin SCHEMBL11407710 | 1.00 | ABCB11 (1.00) | ABCB11CYP1A2HPGDLMNATDP1 | |
| Dicloxacillin SCHEMBL11407708 | 1.00 | ABCB11 (1.00) | ABCB11CYP1A2HPGDLMNATDP1 | |
| Dicloxacillin SCHEMBL5595924 | 0.99 | ABCB11 (0.98) | ABCB11CYP1A2HPGDLMNATDP1 | |
| Dicloxacillin SCHEMBL28540896 | 0.99 | ABCB11 (0.98) | ABCB11CYP1A2HPGDLMNATDP1 | |
| Dicloxacillin SCHEMBL41517 | 0.99 | ABCB11 (0.98) | ABCB11CYP1A2HPGDLMNATDP1 | |
| Dicloxacillin SCHEMBL28536434 | 0.99 | ABCB11 (0.98) | ABCB11CYP1A2HPGDLMNATDP1 | |
| Dicloxacillin SCHEMBL4928524 | 0.99 | ABCB11 (0.98) | ABCB11CYP1A2HPGDLMNATDP1 | |
| Dicloxacillin SCHEMBL5549845 | 0.98 | ABCB11 (0.97) | ABCB11CYP1A2HPGDLMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 28337 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12637481-B2 | Boronic acid derivatives and therapeutic uses thereof | QPEX BIOPHARMA, INC. (US) | 2026-05-26 | — | — | US | claimed |
| WO-2026104587-A1 | CYCLIC BORONIC ACID ESTERS USEFUL AS ADJUVANTS IN THE TREATMENT OF BACTERIAL INFECTIONS | ADJUTEC PHARMA AS (NO) | 2026-05-21 | — | — | WO | claimed |
| WO-2026106917-A1 | EDIBLE TRANSMUCOSAL DRUG DELIVERY METHOD USING AN INTERMEDIATE CAPSULE AS A TEMPORARY VESSEL | BioPhysics Pharma, Inc. (US) | 2026-05-21 | — | — | WO | claimed |
| EP-4739326-A2 | PRODUCTION & SECRETION OF AUXIN-LIKE MOLECULES IN BACTERIA | SNIPR Biome ApS (DK) | 2026-05-13 | — | — | EP | claimed |
| US-20260115234-A1 | PRODUCTION & SECRETION OF AUXIN-LIKE MOLECULES IN BACTERIA | SNIPR BIOME APS (DK) | 2026-04-30 | — | — | US | claimed |
| US-20260108619-A1 | CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2026-04-23 | — | — | US | claimed |
| US-12605345-B2 | Transdermal drug delivery system | BioPhysics Pharma, Inc. (US) | 2026-04-21 | — | — | US | claimed |
| US-20260091089-A1 | Pyocyanine Demethylases and related Phenazine Degrading Agents Compositions, Methods and Systems for Interfering with Viability of Bacteria | CALIFORNIA INST OF TECHN (US) | 2026-04-02 | — | — | US | claimed |
| US-20260092102-A1 | COMPOSITIONS AND METHODS FOR USING BISPECIFIC ANTIBODIES TO BIND COMPLEMENT AND A TARGET ANTIGEN | REGENERON PHARMACEUTICALS, INC. | 2026-04-02 | — | — | US | claimed |
| EP-4712972-A1 | COMBINATION THERAPY FOR BACTERIAL INFECTIONS COMPRISING ZINC-CHELATOR, BETA-LACTAM ANTIBIOTIC AND SERINE BETA-LACTAMASE INHIBITOR | Adjutec Pharma AS (NO) | 2026-03-25 | — | — | EP | claimed |
| US-4376767-A | ANTIBIOTICS AND PHARMACEUTICALS | MERCK & CO., INC. (US) | 1983-03-15 | — | — | US | claimed |
| EP-0056560-A1 | Active antibiotic compositions, process for their manufacture and process for the antibiotic activity of antibiotics | CIBA-GEIGY AG (CH) | 1982-07-28 | — | — | EP | claimed |
| EP-0055870-A1 | Pyridylmethyl esters of selected bio-affecting carboxylic acids, process for preparing and pharmaceutical composition comprising the same | MERCK & CO. INC. (US) | 1982-07-14 | — | — | EP | claimed |
| EP-0051278-A1 | Soft tertiary amine esters of bio-affecting carboxylic acids, processes for preparing and a pharmaceutical composition containing the same | MERCK & CO. INC. (US) | 1982-05-12 | — | — | EP | claimed |
| EP-0050965-A1 | Beta-lactamase inhibitory composition | Takeda Chemical Industries, Ltd. (JP) | 1982-05-05 | — | — | EP | claimed |
| US-4324783-A | SYNERGISTIC COMBINATION OF PENCILLINS | TOYAMA CHEMICAL CO., LTD. (JP) | 1982-04-13 | — | — | US | claimed |
| US-4217274-A | Methoxyethoxymethyl esters of penicillins | BRISTOL-MYERS COMPANY (US) | 1980-08-12 | — | — | US | claimed |
| US-4199566-A | DERIVATIVES OF PENICILLANIC ACID | TOYAMA CHEMICAL COMPANY, LIMITED (JP) | 1980-04-22 | — | — | US | claimed |
| EP-0000891-B1 | SYNERGISTIC COMBINATIONS OF PENICILLINS AND ANTIBIOTIC AGENTS CONTAINING THEM | BAYER AG (DE) | 1980-01-09 | — | — | EP | claimed |
| EP-0000891-A1 | Synergistic combinations of penicillins and antibiotic agents containing them | BAYER AG (DE) | 1979-03-07 | — | — | EP | claimed |