Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19670125 | 0.79 | PTGDR (0.37) | PTGDRXDHARHRH3IRAK4 | |
| SCHEMBL23957566 | 0.78 | HRH3 (0.31) | CYP19A1HRH3 | |
| SCHEMBL18952980 | 0.75 | PTGDR (0.34) | PTGDRXDHARHRH3IRAK4 | |
| SCHEMBL1980154 | 0.73 | IRAK4 (0.36) | PTGDRXDHARIRAK4 | |
| SCHEMBL23926955 | 0.73 | NTRK1 (0.38) | PTGDRXDH | |
| SCHEMBL18952992 | 0.73 | MMP13 (0.39) | PTGDRXDHAR | |
| SCHEMBL17354624 | 0.73 | AR (0.49) | XDHCYP19A1AR | |
| SCHEMBL1980041 | 0.72 | KDM4E (0.48) | XDHCYP19A1AR | |
| SCHEMBL1979015 | 0.71 | AR (0.45) | PTGDRXDHAR | |
| SCHEMBL13832579 | 0.70 | AR (0.36) | PTGDRXDHARIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214090-A1 | KV3 ENHANCERS FOR THE TREATMENT OF COGNITIVE DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2021-10-28 | — | — | WO | disclosed |