⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23957753 | 0.86 | — | — | |
| SCHEMBL23957720 | 0.80 | PDE4A (0.30) | — | |
| SCHEMBL23957657 | 0.77 | ESR2 (0.35) | — | |
| SCHEMBL24581167 | 0.70 | DEGS1 (0.36) | — | |
| SCHEMBL21744590 | 0.68 | ALDH1A1 (0.31) | — | |
| SCHEMBL24444990 | 0.66 | HCAR3 (0.39) | — | |
| SCHEMBL23957728 | 0.65 | — | — | |
| SCHEMBL15785516 | 0.64 | — | — | |
| SCHEMBL14978738 | 0.62 | PTK2 (0.48) | — | |
| SCHEMBL23930236 | 0.61 | GBA1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4141003-A1 | PYRAZOLO[1,5-A]PYRIDINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND COMPOSITION AND USE THEREOF | Shenzhen Zhongge Biological Technology Co., Ltd. (CN) | 2023-03-01 | — | — | EP | disclosed |
| WO-2021213476-A1 | PYRAZOLO[1,5-A]PYRIDINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND COMPOSITION AND USE THEREOF | 深圳晶泰科技有限公司 (CN) | 2021-10-28 | — | — | WO | disclosed |