SCHEMBL23958207 — predicted protein targets

Predicted protein targets (top 18)

	gene	UniProt	supporting neighbours	confidence
▸	GPR6	P46095	1/20	0.37

▸	BRAF	P15056	1/20	0.37

▸	ADORA3	P0DMS8	2/20	0.36

▸	ADORA2A	P29274	2/20	0.36

▸	ADORA1	P30542	2/20	0.36

▸	GRM4	Q14833	2/20	0.36

▸	ALPL	P05186	1/20	0.36

▸	PIK3CD	O00329	1/20	0.35

▸	GRM5	P41594	1/20	0.35

▸	CYP11B1	P15538	2/20	0.34

▸	CYP11B2	P19099	2/20	0.34

▸	ABCG2	Q9UNQ0	1/20	0.34

▸	CHRM4	P08173	1/20	0.34

▸	CYP17A1	P05093	1/20	0.34

▸	NOTUM	Q6P988	1/20	0.34

▸	TDP2	O95551	1/20	0.33

▸	IDO1	P14902	1/20	0.33

▸	SGMS2	Q8NHU3	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30103201	0.86	GPR6 (0.42)	GPR6BRAFPIK3CDABCG2CHRM4
SCHEMBL24111041	0.86	GPR6 (0.42)	GPR6BRAFPIK3CDABCG2CHRM4
SCHEMBL30103276	0.74	PDE7A (0.43)	ABCG2
SCHEMBL23931443	0.74	PDE7A (0.43)	ABCG2
SCHEMBL23958210	0.71	GPR6 (0.41)	GPR6PIK3CDCYP11B1CYP11B2ABCG2
SCHEMBL30103275	0.69	TDO2 (0.48)	IDO1
SCHEMBL23958346	0.69	PDE7A (0.46)	IDO1
SCHEMBL23958208	0.69	TDO2 (0.48)	IDO1
SCHEMBL24111004	0.68	CYP19A1 (0.42)	ALPLABCG2IDO1
SCHEMBL30103182	0.68	CYP19A1 (0.42)	ALPLABCG2IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2021215537-A1	2-HETEROARYLAMINOQUINAZOLINONE DERIVATIVE	大日本住友製薬株式会社 (JP)	2021-10-28	—	—	WO	disclosed