Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.38 |
| ▸ | TDO2 | P48775 | 2/20 | 0.37 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | TEK | Q02763 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24111041 | 1.00 | GPR6 (0.42) | GPR6PIK3CDMAPK14ABCG2TDO2 | |
| SCHEMBL23931443 | 0.89 | PDE7A (0.43) | ABCG2L3MBTL1CSNK2A1 | |
| SCHEMBL30103276 | 0.89 | PDE7A (0.43) | ABCG2L3MBTL1CSNK2A1 | |
| SCHEMBL23958210 | 0.86 | GPR6 (0.41) | GPR6PIK3CDABCG2CSNK2A1 | |
| SCHEMBL23958207 | 0.86 | GPR6 (0.37) | GPR6PIK3CDABCG2BRAFIDO1 | |
| SCHEMBL30103275 | 0.84 | TDO2 (0.48) | TDO2IDO2L3MBTL1IDO1 | |
| SCHEMBL23958208 | 0.84 | TDO2 (0.48) | TDO2IDO2L3MBTL1IDO1 | |
| SCHEMBL30103185 | 0.83 | ABCG2 (0.42) | PIK3CDABCG2CSNK2A1 | |
| SCHEMBL24110797 | 0.83 | ABCG2 (0.42) | PIK3CDABCG2CSNK2A1 | |
| SCHEMBL24111004 | 0.82 | CYP19A1 (0.42) | ABCG2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427399-A | 2-heteroarylaminoquinazolinone derivatives | 住友制药株式会社 | 2022-12-02 | — | — | CN | claimed |
| CN-115427399-A | 2-heteroarylaminoquinazolinone derivatives | 住友制药株式会社 | 2022-12-02 | — | — | CN | disclosed |