Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.32 |
| ▸ | CNR2 | P34972 | 4/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | HRH2 | P25021 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958856 | 0.91 | PGR (0.30) | — | |
| SCHEMBL23958778 | 0.90 | DGAT1 (0.33) | CYP11B1CYP11B2 | |
| SCHEMBL23958709 | 0.89 | FFAR1 (0.31) | — | |
| SCHEMBL23958741 | 0.88 | TACR3 (0.35) | DPP4ALDH1A1 | |
| SCHEMBL23958793 | 0.87 | CFTR (0.35) | CFTRCNR2CYP11B1CYP11B2CNR1 | |
| SCHEMBL26926330 | 0.82 | CFTR (0.39) | CFTRCNR2CNR1ALDH1A1L3MBTL1 | |
| SCHEMBL23958855 | 0.81 | CFTR (0.38) | CFTRCNR2TNIKCNR1ALDH1A1 | |
| SCHEMBL23958626 | 0.81 | CFTR (0.40) | CFTRCNR2TNIKCNR1ALDH1A1 | |
| SCHEMBL23958714 | 0.81 | CFTR (0.40) | CFTRCNR2TNIKCNR1ALDH1A1 | |
| SCHEMBL23958763 | 0.81 | CFTR (0.40) | CFTRCNR2TNIKCNR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023211997-A1 | ANTIVIRAL COMPOUNDS | ENANTA PHARMACEUTICALS, INC. (US) | 2023-11-02 | — | — | WO | disclosed |
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |