Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 3/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | CFTR | P13569 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25687227 | 1.00 | POLB (0.35) | POLBROCK2ROCK1MAPTSYK | |
| SCHEMBL25687225 | 0.94 | CFTR (0.35) | ROCK2ROCK1MAPTCFTR | |
| SCHEMBL25687293 | 0.93 | POLB (0.34) | POLBSYKSSTR5EPHX2 | |
| SCHEMBL30007202 | 0.93 | POLB (0.34) | POLBSYKSSTR5EPHX2 | |
| SCHEMBL23958649 | 0.93 | POLB (0.34) | POLBSYKSSTR5EPHX2 | |
| SCHEMBL25687231 | 0.92 | CNR1 (0.39) | ROCK2ROCK1MAPT | |
| SCHEMBL25233253 | 0.92 | CNR1 (0.39) | ROCK2ROCK1MAPT | |
| SCHEMBL30006737 | 0.92 | CNR1 (0.39) | ROCK2ROCK1MAPT | |
| SCHEMBL25242930 | 0.91 | GABRA5 (0.37) | ROCK2ROCK1PDE4B | |
| SCHEMBL30007933 | 0.91 | GABRA5 (0.37) | ROCK2ROCK1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |