Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.37 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12490922 | 0.68 | HCAR1 (0.37) | MAPK14MAPK13MAPK12MAPK11KCNH2 | |
| SCHEMBL23930180 | 0.66 | ERBB2 (0.42) | CHUKADORA2AADORA1PDE3BPDE3A | |
| SCHEMBL28988564 | 0.65 | MAOB (0.43) | CHUKADORA2AADORA1PDE3BPDE3A | |
| SCHEMBL21283226 | 0.63 | CNR2 (0.50) | MAPK14CHUKADORA2AADORA1ADORA2B | |
| SCHEMBL16321240 | 0.62 | ADORA1 (0.71) | CHUKADORA2AADORA1ADORA2BCSNK2A1 | |
| SCHEMBL22180269 | 0.60 | CHUK (0.46) | CHUKADORA2AADORA1ADORA2BCSNK2A1 | |
| SCHEMBL21911775 | 0.60 | KDM4C (0.30) | KDM4C | |
| SCHEMBL30364487 | 0.59 | FAAH (0.44) | MAPK14ADORA2AADORA1ALDH1A1MAPT | |
| SCHEMBL20001703 | 0.59 | ADORA2A (0.33) | ADORA2AADORA1ADORA2BALDH1A1KDM4E | |
| SCHEMBL22082173 | 0.58 | PTK2 (0.43) | MAPK14ALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |