Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | PI4KA | P42356 | 1/20 | 0.43 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.39 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22522218 | 0.83 | XDH (0.46) | MGLLKMT2ATET2TET1GAA | |
| SCHEMBL12490922 | 0.80 | HCAR1 (0.37) | MGLLMAPK14ALDH1A1MAPTLMNA | |
| SCHEMBL22468302 | 0.80 | TET2 (0.60) | FAAHMGLLTET2TET1ALDH1A1 | |
| SCHEMBL2113288 | 0.80 | SMN1; SMN2 (0.52) | KMT2ATET2TET1GAAALDH1A1 | |
| SCHEMBL22386334 | 0.78 | ROCK2 (0.40) | KMT2ATET2TET1GAAALDH1A1 | |
| SCHEMBL22522557 | 0.76 | ALDH1A1 (0.46) | TET2TET1GAAALDH1A1POLB | |
| SCHEMBL22421219 | 0.74 | CYP2A6 (0.44) | PI4KAPI4K2BPI4K2API4KBL3MBTL1 | |
| SCHEMBL22386367 | 0.73 | ALDH1A1 (0.42) | TET2TET1ALDH1A1ROCK2LMNA | |
| SCHEMBL24017805 | 0.73 | HCAR1 (0.42) | KMT2AGAAALDH1A1POLBMAPT | |
| SCHEMBL22236033 | 0.73 | PDE4D (0.32) | KMT2AROCK2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064223-A1 | TRI-SUBSTITUTED PYRIDINES | GOSSAMER BIO SERVICES, INC. (US) | 2023-04-20 | — | — | WO | disclosed |