Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 11/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958859 | 0.81 | CFTR (0.34) | CTSAROCK2ROCK1ALDH1A1POLB | |
| SCHEMBL23958874 | 0.78 | CTSA (0.35) | CTSAROCK2ROCK1HPGD | |
| SCHEMBL23958990 | 0.78 | CFTR (0.33) | ROCK2ROCK1ALDH1A1POLB | |
| SCHEMBL25698133 | 0.78 | PDE4B (0.35) | ROCK2ROCK1 | |
| SCHEMBL30006992 | 0.72 | CTSA (0.35) | CTSAROCK2ROCK1 | |
| SCHEMBL23958639 | 0.72 | CTSA (0.35) | CTSAROCK2ROCK1 | |
| SCHEMBL23958805 | 0.72 | CTSA (0.35) | CTSAROCK2ROCK1 | |
| SCHEMBL25697249 | 0.72 | CETP (0.34) | CTSAROCK2ROCK1 | |
| SCHEMBL23958966 | 0.71 | GABRA5 (0.33) | CTSA | |
| SCHEMBL25698156 | 0.71 | PDE4B (0.34) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |