Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958966 | 0.93 | GABRA5 (0.33) | CTSAGABRA5 | |
| SCHEMBL23958797 | 0.85 | CFTR (0.36) | GABRA5ROCK2ROCK1ACSS2PDE4B | |
| SCHEMBL23958652 | 0.85 | LMNA (0.33) | FFAR1ROCK2ROCK1ACSS2 | |
| SCHEMBL23958776 | 0.85 | LMNA (0.36) | FFAR1ROCK2ROCK1PDE4B | |
| SCHEMBL23958656 | 0.84 | SSTR5 (0.34) | — | |
| SCHEMBL25698171 | 0.84 | PDE4B (0.31) | ACSS2PDE4B | |
| SCHEMBL25242930 | 0.82 | GABRA5 (0.37) | CTSAGABRA5ROCK2ROCK1PDE4B | |
| SCHEMBL30007933 | 0.82 | GABRA5 (0.37) | CTSAGABRA5ROCK2ROCK1PDE4B | |
| SCHEMBL25687233 | 0.82 | GABRA5 (0.37) | CTSAGABRA5ROCK2ROCK1PDE4B | |
| SCHEMBL23958859 | 0.82 | CFTR (0.34) | CTSAROCK2ROCK1ACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |