Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 4/20 | 0.35 |
| ▸ | MMP1 | P03956 | 3/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958823 | 0.92 | MMP13 (0.42) | CNR1MMP13MMP1MMP2MMP9 | |
| SCHEMBL23958718 | 0.91 | CNR1 (0.44) | CNR1MMP13MMP1PPARGPPARA | |
| SCHEMBL30007475 | 0.73 | CFTR (0.41) | CNR1KDM4EMAPT | |
| SCHEMBL23958619 | 0.73 | CFTR (0.41) | CNR1KDM4EMAPT | |
| SCHEMBL28909146 | 0.71 | MAPT (0.40) | MMP13MMP1MMP2MMP9THRB | |
| SCHEMBL30211226 | 0.69 | MAPT (0.37) | MMP13MMP1MMP2MMP9THRB | |
| SCHEMBL23958824 | 0.69 | MAPT (0.37) | MMP13MMP1MMP2MMP9THRB | |
| SCHEMBL23958842 | 0.67 | MAPT (0.38) | MMP13MMP1MMP2MMP9THRB | |
| SCHEMBL23958867 | 0.63 | CFTR (0.32) | — | |
| SCHEMBL23958693 | 0.61 | CFTR (0.40) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |