Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.37 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958823 | 0.93 | MMP13 (0.42) | CNR1MMP1MMP13MEP1BDHODH | |
| SCHEMBL23958724 | 0.91 | CNR1 (0.35) | CNR1MMP1MMP13PPARAMEP1B | |
| SCHEMBL30007475 | 0.74 | CFTR (0.41) | CNR1DHODHKDM4E | |
| SCHEMBL23958619 | 0.74 | CFTR (0.41) | CNR1DHODHKDM4E | |
| SCHEMBL28909146 | 0.72 | MAPT (0.40) | MMP1MMP13DHODHMEN1HTT | |
| SCHEMBL30211226 | 0.69 | MAPT (0.37) | MMP1MMP13MEN1KMT2A | |
| SCHEMBL23958824 | 0.69 | MAPT (0.37) | MMP1MMP13MEN1KMT2A | |
| SCHEMBL23958842 | 0.67 | MAPT (0.38) | MMP1MMP13 | |
| SCHEMBL17083312 | 0.64 | MEP1B (0.55) | PPARAMEP1BCYP2C19PPARGMEN1 | |
| SCHEMBL23958650 | 0.64 | ALDH1A1 (0.41) | KDM4EHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |