Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | GCGR | P47871 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958765 | 1.00 | CFTR (0.34) | CFTRBRAFCDK8CDK5CLK4 | |
| SCHEMBL23958860 | 0.80 | RPS6KB1 (0.33) | CFTRBRAFCDK8CDK5CLK4 | |
| SCHEMBL23958800 | 0.79 | KDM5B (0.32) | CFTRCDK8CDK5CLK4KDM5B | |
| SCHEMBL23958763 | 0.77 | CFTR (0.40) | CFTRKDM4EALDH1A1LMNA | |
| SCHEMBL23958626 | 0.77 | CFTR (0.40) | CFTRKDM4EALDH1A1LMNA | |
| SCHEMBL25686730 | 0.76 | CFTR (0.35) | CFTRBRAFCDK8CDK5CLK4 | |
| SCHEMBL23958689 | 0.74 | CFTR (0.35) | CFTRMEN1KMT2ATGFBR1KDM4E | |
| SCHEMBL23958729 | 0.74 | CFTR (0.35) | CFTRMEN1KMT2ATGFBR1KDM4E | |
| SCHEMBL23958643 | 0.74 | CFTR (0.35) | CFTRMEN1KMT2ATGFBR1KDM4E | |
| SCHEMBL30006775 | 0.74 | CFTR (0.35) | CFTRMEN1KMT2ATGFBR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |