Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.33 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.31 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | BRAF | P15056 | 1/20 | 0.30 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958765 | 0.80 | CFTR (0.34) | CFTRMAPK14BRAFCDK8CDK5 | |
| SCHEMBL23958730 | 0.80 | CFTR (0.34) | CFTRMAPK14BRAFCDK8CDK5 | |
| SCHEMBL23958627 | 0.79 | CFTR (0.36) | RPS6KB1TNIKSLC34A1HRH2HRH3 | |
| SCHEMBL25686999 | 0.76 | SLC34A1 (0.33) | SLC34A1HRH2HRH3CFTRHTR2A | |
| SCHEMBL25687000 | 0.76 | SLC34A1 (0.33) | SLC34A1HRH2HRH3CFTRHTR2A | |
| SCHEMBL30007885 | 0.76 | SLC34A1 (0.33) | SLC34A1HRH2HRH3CFTRHTR2A | |
| SCHEMBL23958787 | 0.76 | SLC34A1 (0.33) | SLC34A1HRH2HRH3CFTRHTR2A | |
| SCHEMBL23958756 | 0.75 | SLC34A1 (0.33) | SLC34A1 | |
| SCHEMBL25686730 | 0.71 | CFTR (0.35) | TNIKCFTRBRAFCDK8CDK5 | |
| SCHEMBL25691242 | 0.70 | MAPT (0.32) | SLC34A1HRH2HRH3CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |