Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 3/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958765 | 0.79 | CFTR (0.34) | KDM5BCFTRCDK8CDK5CLK4 | |
| SCHEMBL23958730 | 0.79 | CFTR (0.34) | KDM5BCFTRCDK8CDK5CLK4 | |
| SCHEMBL23958763 | 0.64 | CFTR (0.40) | CFTRADORA2AADORA1 | |
| SCHEMBL23958626 | 0.64 | CFTR (0.40) | CFTRADORA2AADORA1 | |
| SCHEMBL23958860 | 0.62 | RPS6KB1 (0.33) | CFTRCDK8CDK5CLK4 | |
| SCHEMBL12490922 | 0.61 | HCAR1 (0.37) | — | |
| SCHEMBL23958593 | 0.60 | CFTR (0.39) | CFTRADORA2AADORA1 | |
| SCHEMBL23958679 | 0.60 | MAPK14 (0.37) | ADORA2AADORA1 | |
| SCHEMBL23958714 | 0.60 | CFTR (0.40) | CFTRADORA2AADORA1 | |
| SCHEMBL25686730 | 0.58 | CFTR (0.35) | KDM5BCFTRCDK8CDK5CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |