Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25689076 | 0.89 | — | — | |
| SCHEMBL23958855 | 0.88 | CFTR (0.38) | CFTRSCN9ACNR2TNIKFPR2 | |
| SCHEMBL28909215 | 0.79 | CFTR (0.38) | CFTRSCN9ACNR2TNIKFPR2 | |
| SCHEMBL23958642 | 0.74 | CFTR (0.38) | CFTRCNR2TNIK | |
| SCHEMBL26926330 | 0.74 | CFTR (0.39) | CFTRSCN9ACNR2 | |
| SCHEMBL23958714 | 0.72 | CFTR (0.40) | CFTRSCN9ACNR2TNIKFPR2 | |
| SCHEMBL23958763 | 0.72 | CFTR (0.40) | CFTRSCN9ACNR2TNIKFPR2 | |
| SCHEMBL23958626 | 0.72 | CFTR (0.40) | CFTRSCN9ACNR2TNIKFPR2 | |
| SCHEMBL23958593 | 0.70 | CFTR (0.39) | CFTRCNR2 | |
| SCHEMBL23958627 | 0.70 | CFTR (0.36) | CFTRCNR2TNIK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |