Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | SSTR5 | P35346 | 3/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | GPR6 | P46095 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | CCR3 | P51677 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958656 | 0.88 | SSTR5 (0.34) | IRAK4SSTR5KCNH2HRH1CCR3 | |
| SCHEMBL23958966 | 0.87 | GABRA5 (0.33) | IRAK4AR | |
| SCHEMBL23958810 | 0.85 | CFTR (0.34) | P2RX7LMNAMAPTCFTR | |
| SCHEMBL25687266 | 0.83 | CFTR (0.34) | ARSSTR5KCNH2GPR6LMNA | |
| SCHEMBL25687285 | 0.83 | CNR1 (0.34) | ARSSTR5KCNH2GPR6LMNA | |
| SCHEMBL30006884 | 0.83 | CNR1 (0.34) | ARSSTR5KCNH2GPR6LMNA | |
| SCHEMBL25280037 | 0.83 | CFTR (0.34) | ARSSTR5KCNH2GPR6LMNA | |
| SCHEMBL23958990 | 0.83 | CFTR (0.33) | P2RX7KCNH2LMNAMAPTCFTR | |
| SCHEMBL23958753 | 0.82 | CFTR (0.32) | CFTR | |
| SCHEMBL23958726 | 0.81 | CFTR (0.35) | NR1I2LMNAMAPTCFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |