Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 9/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958797 | 0.94 | CFTR (0.36) | CFTRP2RX7LMNATP53PDE4B | |
| SCHEMBL23958990 | 0.87 | CFTR (0.33) | CFTRP2RX7LMNATP53DDR1 | |
| SCHEMBL23958786 | 0.85 | IRAK4 (0.32) | CFTRP2RX7LMNAMAPT | |
| SCHEMBL23958776 | 0.84 | LMNA (0.36) | CFTRP2RX7LMNATP53PDE4B | |
| SCHEMBL23958652 | 0.84 | LMNA (0.33) | CFTRLMNATP53MAPTSMN1; SMN2 | |
| SCHEMBL25698156 | 0.84 | PDE4B (0.34) | P2RX7PDE4B | |
| SCHEMBL25687507 | 0.83 | CFTR (0.36) | CFTRP2RX7PDE4BHCRTR1HCRTR2 | |
| SCHEMBL28909199 | 0.83 | CFTR (0.36) | CFTRP2RX7PDE4BHCRTR1HCRTR2 | |
| SCHEMBL23958726 | 0.81 | CFTR (0.35) | CFTRLMNATP53MAPTSMN1; SMN2 | |
| SCHEMBL25687501 | 0.81 | CFTR (0.39) | CFTRDDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |