Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 5/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | SLC34A1 | Q06495 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | CFTR | P13569 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23930265 | 0.87 | ADORA2A (0.40) | ADORA2AADORA1ADORA2BADORA3MAPK14 | |
| SCHEMBL23930153 | 0.87 | ADORA2A (0.40) | ADORA2AADORA1ADORA2BADORA3MAPK14 | |
| SCHEMBL30007319 | 0.87 | ADORA2A (0.40) | ADORA2AADORA1ADORA2BADORA3MAPK14 | |
| SCHEMBL23958683 | 0.78 | ADORA2A (0.39) | ADORA2AADORA1ADORA2BADORA3DHODH | |
| SCHEMBL31309443 | 0.75 | ADORA2A (0.43) | ADORA2AADORA1ADORA2BADORA3MAPK14 | |
| SCHEMBL26728890 | 0.73 | ADORA2A (0.40) | ADORA2AADORA1ADORA2BADORA3CFTR | |
| SCHEMBL24363599 | 0.72 | ALOX5 (0.46) | ADORA2AADORA1ADORA2BADORA3DHODH | |
| SCHEMBL26728887 | 0.71 | ADORA1 (0.38) | ADORA2AADORA1ADORA2BADORA3MAPK14 | |
| SCHEMBL30007134 | 0.71 | SLC34A1 (0.36) | ADORA2AADORA1ADORA2BADORA3DHODH | |
| SCHEMBL25686851 | 0.71 | SLC34A1 (0.36) | ADORA2AADORA1ADORA2BADORA3DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |