Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PBRM1 | Q86U86 | 3/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29242291 | 0.84 | MAPT (0.40) | MAPTTP53POLBPBRM1CYP1A2 | |
| SCHEMBL29242336 | 0.79 | TP53 (0.41) | MAPTTP53POLBPBRM1GABRA1 | |
| SCHEMBL29242341 | 0.78 | HAO1 (0.42) | MAPTTP53POLBALDH1A1NQO2 | |
| SCHEMBL281695 | 0.73 | RAB9A (0.48) | MAPTTP53POLBMAPK1LMNA | |
| SCHEMBL31219834 | 0.73 | PGR (0.45) | MAPTTP53POLBGABRA1GABRA5 | |
| SCHEMBL2239581 | 0.73 | PGR (0.45) | MAPTTP53POLBGABRA1GABRA5 | |
| SCHEMBL29242289 | 0.72 | TP53 (0.49) | MAPTTP53POLBCYP1A2LMNA | |
| SCHEMBL30965337 | 0.72 | TP53 (0.49) | MAPTTP53POLBCYP1A2LMNA | |
| SCHEMBL9802951 | 0.72 | DDB1 (0.49) | PBRM1DDB1CRBNTNKS2ALDH1A1 | |
| SCHEMBL16668782 | 0.72 | CMA1 (0.43) | MAPTTP53POLBCYP1A2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021212974-A1 | RACEMIC AND CHIRAL 3-(2,3-BUTADIENYL)OXYINDOLINONE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 复旦大学 (CN) | 2021-10-28 | — | — | WO | disclosed |