Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GLS | O94925 | 2/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | AKT1 | P31749 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6811825 | 0.81 | GLS (0.65) | EPHX2CA12CA1CA7CA14 | |
| SCHEMBL6180339 | 0.80 | CA12 (0.52) | EPHX2IDO1CA12CA1CA7 | |
| SCHEMBL10385979 | 0.80 | IDO1 (0.48) | IDO1CA12CA1CA7CA14 | |
| SCHEMBL9608852 | 0.80 | SIGMAR1 (0.46) | IDO1CA12CA1CA7CA14 | |
| SCHEMBL8467720 | 0.79 | MAOB (0.49) | IDO1CA12CA1CA7CA14 | |
| SCHEMBL5158237 | 0.79 | MAOB (0.49) | IDO1CA12CA1CA7CA14 | |
| SCHEMBL4583679 | 0.79 | IDO1 (0.53) | IDO1CA12CA1CA7CA14 | |
| SCHEMBL18487257 | 0.79 | TDP1 (0.50) | IDO1CA12CA1CA7KMT2A | |
| SCHEMBL18262007 | 0.79 | TDP1 (0.50) | IDO1CA12CA1CA7KMT2A | |
| SCHEMBL18262010 | 0.79 | TDP1 (0.50) | IDO1CA12CA1CA7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021217041-A1 | N-SUBSTITUTED ALPHA-AMINO AND ALPHA-HYDROXY CARBOXAMIDE DERIVATIVES | IMMVENTION THERAPEUTIX (US) | 2021-10-28 | — | — | WO | disclosed |