Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL341470 | 0.76 | SMN1; SMN2 (0.39) | RAB9AKDM4EALDH1A1 | |
| SCHEMBL8074924 | 0.72 | HSD17B10 (0.47) | KDM4EALDH1A1 | |
| SCHEMBL4138147 | 0.67 | HSD17B10 (0.50) | RAB9AKDM4ELMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL19148315 | 0.65 | HSD17B10 (0.48) | RAB9AKDM4ELMNAALDH1A1 | |
| SCHEMBL12550940 | 0.64 | GLA (0.53) | RAB9AKDM4ELMNAALDH1A1 | |
| SCHEMBL2659976 | 0.63 | GNAI3 (0.56) | LMNAALDH1A1 | |
| SCHEMBL12820702 | 0.62 | RAB9A (0.30) | RAB9A | |
| SCHEMBL1291195 | 0.62 | RAB9A (0.43) | RAB9AKDM4ELMNAALDH1A1 | |
| SCHEMBL8979916 | 0.62 | RAB9A (0.34) | RAB9AALDH1A1 | |
| SCHEMBL16385919 | 0.61 | RAB9A (0.35) | RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159586-A1 | INHIBITORS OF HUMAN EPIDIDYMUS PROTEIN 4 | UNIVERSITY OF ROCHESTER | 2023-05-25 | — | — | US | disclosed |
| US-20230159586-A1 | INHIBITORS OF HUMAN EPIDIDYMUS PROTEIN 4 | UNIVERSITY OF ROCHESTER | 2023-05-25 | — | — | US | disclosed |
| WO-2021216670-A1 | INHIBITORS OF HUMAN EPIDIDYMUS PROTEIN 4 | UNIVERSITY OF ROCHESTER (US) | 2021-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159586-A1 | INHIBITORS OF HUMAN EPIDIDYMUS PROTEIN 4 | MAN2B2, NASP, BRDT | RAB9A 3411/4885KDM4E 2574/4885LMNA 4018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.