Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | WNT3 | P56703 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23959845 | 0.82 | CYP1A2 (0.63) | CYP1A2CYP3A4TDP1POLBMEN1 | |
| SCHEMBL31321007 | 0.82 | WNT3 (0.66) | CYP1A2CYP3A4TDP1POLBMEN1 | |
| SCHEMBL22264710 | 0.82 | WNT3 (0.66) | CYP1A2CYP3A4TDP1POLBMEN1 | |
| SCHEMBL31406374 | 0.77 | ALDH1A1 (0.61) | TDP1POLBMEN1KMT2ACASP3 | |
| SCHEMBL28400031 | 0.77 | ALDH1A1 (0.65) | TDP1POLBMEN1KMT2ACASP3 | |
| SCHEMBL16456024 | 0.76 | WNT3 (0.60) | TDP1POLBMEN1KMT2ACASP3 | |
| SCHEMBL16456004 | 0.76 | WNT3 (0.60) | TDP1POLBMEN1KMT2ACASP3 | |
| SCHEMBL28400036 | 0.75 | ALDH1A1 (0.67) | TDP1POLBMEN1KMT2ACASP3 | |
| SCHEMBL27599095 | 0.74 | TDP1 (0.67) | CYP1A2CYP3A4TDP1POLBMEN1 | |
| SCHEMBL6720632 | 0.74 | CYP1A2 (0.65) | CYP1A2CYP3A4TDP1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210332038-A1 | 6H-IMIDAZO[4,5,1-ij]QUINOLONE, SYNTHESIS METHOD AND USE THEREOF | HANGZHOU NORMAL UNIVERSITY | 2021-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210332038-A1 | 6H-IMIDAZO[4,5,1-ij]QUINOLONE, SYNTHESIS METHOD AND USE THEREOF | ABL1, KCNK4, KCNJ4 | CYP1A2 239/4885CYP3A4 20/4885TDP1 4114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.