SCHEMBL239600

SCHEMBL239600

COc1ccc2c(c1)Nc1ccccc1S2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 12/20 1.00
MAPT P10636 8/20 0.81
GAA P10253 7/20 0.81
KMT2A Q03164 6/20 0.81
MEN1 O00255 5/20 0.81
TDP1 Q9NUW8 3/20 0.81
MAPK1 P28482 2/20 0.81
LMNA P02545 2/20 0.81
HTT P42858 2/20 0.81
SMN1; SMN2 Q16637 2/20 0.81
L3MBTL1 Q9Y468 2/20 0.81
SNCA P37840 5/20 0.66
NPC1 O15118 2/20 0.61
RAB9A P51151 2/20 0.61
NPSR1 Q6W5P4 1/20 0.61
ALOX15 P16050 3/20 0.59
BCHE P06276 2/20 0.59
ACHE P22303 2/20 0.59
POLB P06746 2/20 0.59
MAOA P21397 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenothiazine SCHEMBL9074312 1.00 NOX1 (1.00) NOX1MAPTGAAKMT2AMEN1
Benzene SCHEMBL29242182 0.98 NOX1 (0.97) NOX1MAPTGAAKMT2AMEN1
SCHEMBL1853042 0.91 NOX1 (0.83) NOX1MAPTGAAKMT2AMEN1
SCHEMBL4080414 0.90 NOX1 (1.00) NOX1MAPTGAAKMT2AMEN1
SCHEMBL22960496 0.82 NOX1 (0.69) NOX1MAPTGAAKMT2AMEN1
SCHEMBL22960437 0.82 NOX1 (0.68) NOX1MAPTGAAKMT2AMEN1
SCHEMBL11580137 0.82 NOX1 (0.69) NOX1MAPTGAAKMT2AMEN1
SCHEMBL11581150 0.82 NOX1 (0.69) NOX1MAPTGAAKMT2AMEN1
SCHEMBL3175562 0.82 NOX1 (0.68) NOX1MAPTGAAKMT2AMEN1
SCHEMBL3176131 0.82 NOX1 (0.68) NOX1MAPTGAAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 365 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250255879-A1 PHARMACEUTICAL COMPOSITION FOR ANTI-CANCER COMPRISING NUPR1 ISOFORM A INHIBITOR SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2025-08-14 US claimed
CN-119931160-B Preparation method of antibacterial starch-based material 佛山市富实新高分子纤维有限公司 2025-06-13 CN claimed
CN-120064231-A Preparation and application of hypochlorite dual-mode sensing platform 南京林业大学 2025-05-30 CN claimed
CN-119931160-A Preparation method of antibacterial starch-based material 佛山市富实新高分子纤维有限公司 2025-05-06 CN claimed
CN-119823148-A Hypochlorous acid fluorescent probe based on phenothiazine skeleton, and preparation and application thereof 西北师范大学 2025-04-15 CN claimed
CN-119751477-A Lipid drop and hypochlorous acid sequence response type fluorescent probe and synthetic method and application thereof 南宁师范大学 2025-04-04 CN claimed
CN-118290599-A Cellulose-based fluorescent probe for hypochlorous acid detection and preparation method and application thereof 齐鲁工业大学(山东省科学院) 2024-07-05 CN claimed
CN-117964613-A Compound, preparation and application thereof in ratio detection hypochlorous acid fluorescence sensor 山西大同大学 2024-05-03 CN claimed
CN-117700431-A Large Stokes displacement near infrared fluorescent probe for detecting HClO, preparation method and biological imaging application thereof 河南中医药大学 2024-03-15 CN claimed
CN-115368415-B ClO-/H in detection line granule 2 O 2 Multicolor fluorescent probe of (2), preparation method and application thereof 徐州医科大学 2024-03-12 CN claimed
US-20170009089-A1 ACTIVE ENERGY RAY-CURABLE INKJET INK COMPOSITION AND PRINTED PRODUCT DNP FINE CHEMICALS CO LTD (JP) 2017-01-12 US claimed
US-7897311-B2 Phenothiazine containing photogenerating layer photoconductors XEROX CORPORATION (US) 2011-03-01 US claimed
US-20090274969-A1 PHENOTHIAZINE CONTAINING PHOTOGENERATING LAYER PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-11-05 US claimed
US-20070265208-A1 Association of calpain inhibitors and reactive oxygen species trapping agents SOCIETE DE CONSEILS DE RECHERCHE ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) 2007-11-15 US claimed
US-7244711-B2 Association of calpain inhibitors and reactive oxygen species trapping agents SOCIETE DE CONSEILS DE RECHERCHES ET D' 'APPLICATIONS SCIENTIFIQUES S.C.R.A.S (FR) 2007-07-17 US claimed
EP-1337269-B1 ASSOCIATION OF CALPAIN INHIBITORS AND REACTIVE OXYGEN SPECIES TRAPPING AGENTS SOD CONSEILS RECH APPLIC (FR) 2006-11-08 EP claimed
US-20040053851-A1 Association of calpain inhibitors and reactive oxygen species trapping agents IPSEN PHARMA S.A.S. (FR) 2004-03-18 US claimed
EP-1337269-A2 ASSOCIATION OF CALPAIN INHIBITORS AND REACTIVE OXYGEN SPECIES TRAPPING AGENTS SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A. (FR) 2003-08-27 EP claimed
WO-2002040016-A2 ASSOCIATION OF CALPAIN INHIBITORS AND REACTIVE OXYGEN SPECIES TRAPPING AGENTS SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) 2002-05-23 WO claimed
US-4249003-A Process for polycyclic amines AKTIEBOLAGET LEO (SE) 1981-02-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070265208-A1 Association of calpain inhibitors and reactive oxygen species trapping agents CAPNS1, CAPN1, CAPN2 NOX1 580/4885MAPT 282/4885GAA 589/4885
US-20040053851-A1 Association of calpain inhibitors and reactive oxygen species trapping agents CAPN2, CAPN1, CAPN9 NOX1 80/4885MAPT 225/4885GAA 352/4885
US-20250255879-A1 PHARMACEUTICAL COMPOSITION FOR ANTI-CANCER COMPRISING NUPR1 ISOFORM A INHIBITOR NUP205, NUP188, NUP50 NOX1 3568/4885MAPT 2909/4885GAA 2915/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.