SCHEMBL4080414

SCHEMBL4080414

COc1ccc2c(c1)Sc1ccccc1N2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 11/20 1.00
MAPT P10636 7/20 1.00
GAA P10253 6/20 1.00
KMT2A Q03164 5/20 1.00
MEN1 O00255 4/20 1.00
MAPK1 P28482 2/20 1.00
TDP1 Q9NUW8 2/20 1.00
HTT P42858 2/20 1.00
SMN1; SMN2 Q16637 2/20 1.00
L3MBTL1 Q9Y468 2/20 1.00
LMNA P02545 1/20 1.00
SNCA P37840 6/20 0.83
NPC1 O15118 2/20 0.61
RAB9A P51151 2/20 0.61
NPSR1 Q6W5P4 1/20 0.61
MAOA P21397 2/20 0.59
POLB P06746 2/20 0.59
BCHE P06276 2/20 0.59
ACHE P22303 2/20 0.59
ALOX15 P16050 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3489840 0.91 SNCA (1.00) NOX1MAPTGAAKMT2AMEN1
SCHEMBL29636455 0.91 SNCA (1.00) NOX1MAPTGAAKMT2AMEN1
Phenothiazine SCHEMBL9074312 0.90 NOX1 (1.00) NOX1MAPTGAAKMT2AMEN1
SCHEMBL239600 0.90 NOX1 (1.00) NOX1MAPTGAAKMT2AMEN1
Benzene SCHEMBL29242182 0.88 NOX1 (0.97) NOX1MAPTGAAKMT2AMEN1
SCHEMBL17289246 0.83 SNCA (0.83) NOX1MAPTGAAKMT2AMEN1
SCHEMBL8746975 0.82 NOX1 (0.69) NOX1MAPTGAAKMT2AMEN1
SCHEMBL8879433 0.82 MAPT (0.68) NOX1MAPTGAAKMT2AMEN1
SCHEMBL9007338 0.82 MAPT (0.68) NOX1MAPTGAAKMT2AMEN1
SCHEMBL1853042 0.82 NOX1 (0.83) NOX1MAPTGAAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024214816-A1 PHOTOSENSITIVE RESIN LAMINATE AND METHOD FOR FORMING RESIST PATTERN 旭化成株式会社 2024-10-17 WO disclosed
EP-2998303-B1 PHENOTHIAZINE DERIVATIVES AND METHODS FOR TREATING TUMORS B & G PARTNERS LLC (US) 2018-06-13 EP disclosed
EP-2998303-A1 PHENOTHIAZINE DERIVATIVES AND METHODS FOR TREATING TUMORS B & G Partners, LLC (US) 2016-03-23 EP disclosed
US-9198916-B1 Compounds and methods for treating tumors B&G PARTNERS, LLC (US) 2015-12-01 US disclosed
CN-101614957-A Be used for forming radiation sensitive compositions, color filter and the solid-state imager of solid-state imager with color filter JSR CORP 2009-12-30 CN disclosed
EP-2012182-A2 Radiation-sensitive composition for forming color filter for solid-state image sensing device, color filter, and solid-state image sensing device JSR Corporation (JP) 2009-01-07 EP disclosed
US-20090004578-A1 RADIATION-SENSITIVE COMPOSITION FOR FORMING COLOR FILTER FOR SOLID-STATE IMAGE SENSING DEVICE, COLOR FILTER, AND SOLID-STATE IMAGE SENSING DEVICE JSR CORPORATION (JP) 2009-01-01 US disclosed