Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.41 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.36 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | POLG | P54098 | 1/20 | 0.35 |
| ▸ | P2RY2 | P41231 | 9/20 | 0.35 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.34 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23047607 | 0.87 | POLRMT (0.53) | POLRMTP2RX3P2RX2P2RX4POLG | |
| SCHEMBL24340456 | 0.87 | POLRMT (0.53) | POLRMTP2RX3P2RX2P2RX4POLG | |
| SCHEMBL24340455 | 0.85 | POLRMT (0.50) | POLRMTP2RX3P2RX2P2RX4POLG | |
| SCHEMBL23959828 | 0.78 | CYP2A6 (0.38) | — | |
| SCHEMBL22355531 | 0.77 | POLRMT (0.43) | POLRMTP2RY2P2RY1 | |
| SCHEMBL24340458 | 0.77 | POLRMT (0.43) | POLRMTP2RY2P2RY1 | |
| SCHEMBL23960110 | 0.73 | POLRMT (0.57) | POLRMTP2RX3P2RX2P2RX4P2RY2 | |
| SCHEMBL25821576 | 0.71 | TMPRSS2 (0.51) | POLRMTGPR17P2RX3P2RX2P2RX4 | |
| SCHEMBL20059049 | 0.71 | POLRMT (0.55) | POLRMTP2RX3P2RX2P2RX4POLG | |
| SCHEMBL24982214 | 0.70 | PDE2A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021213288-A1 | ANTIVIRAL APPLICATION OF NUCLEOSIDE ANALOG OR COMBINATION FORMULATION CONTAINING NUCLEOSIDE ANALOG | 中国科学院上海药物研究所 (CN) | 2021-10-28 | — | — | WO | disclosed |