Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A3 | P38919 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1003199 | 0.87 | POLB (0.46) | POLBFABP3FABP4CYP1A2GABRA1 | |
| SCHEMBL1725337 | 0.78 | DGAT1 (0.47) | POLBPTGS2CYP1A2 | |
| SCHEMBL17831137 | 0.77 | POLB (0.44) | POLBCYP1A2 | |
| SCHEMBL18589768 | 0.77 | ADRB2 (0.42) | EIF4A3FABP3FABP4 | |
| SCHEMBL20173746 | 0.75 | FABP3 (0.61) | EIF4A3FABP3FABP4AKR1C3AKR1C2 | |
| SCHEMBL5952491 | 0.74 | POLB (0.50) | POLBAPPPTGS2CYP1A2PTGS1 | |
| SCHEMBL20429953 | 0.73 | EIF4A3 (0.41) | EIF4A3POLBFABP3FABP4AKR1C3 | |
| SCHEMBL14696545 | 0.73 | POLB (0.41) | POLBCYP1A2GABRA1GABRB2 | |
| SCHEMBL22945695 | 0.72 | FABP3 (0.47) | FABP3FABP4GABRA1GABRB2TRPA1 | |
| SCHEMBL22358741 | 0.71 | FABP3 (0.52) | EIF4A3FABP3FABP4AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021216705-A1 | GPR52 MODULATORS AND METHODS OF USE | NEUROCRINE BIOSCIENCES, INC. (US) | 2021-10-28 | — | — | WO | disclosed |