Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 2/20 | 0.47 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | LDHB | P07195 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1003199 | 0.80 | POLB (0.46) | FABP3FABP4TRPA1PTGS1CACNA1C | |
| SCHEMBL22946243 | 0.79 | BCHE (0.45) | FABP3FABP4CYP3A4MEN1KMT2A | |
| SCHEMBL2383444 | 0.77 | FABP4 (0.69) | FABP3FABP4CYP3A4HPGDMEN1 | |
| SCHEMBL1003964 | 0.77 | FABP3 (0.42) | FABP3FABP4TRPA1PTGS1CACNA1C | |
| SCHEMBL3125411 | 0.76 | MEN1 (0.41) | CYP3A4HPGDMEN1KMT2AKDM4E | |
| SCHEMBL698413 | 0.75 | KDM4E (0.46) | CYP3A4HPGDMEN1KMT2AKDM4E | |
| SCHEMBL19546738 | 0.74 | FABP3 (0.58) | FABP3FABP4TRPA1PTGS1CACNA1C | |
| SCHEMBL2380154 | 0.73 | CYP3A4 (0.61) | CYP3A4HPGDMEN1KMT2ALMNA | |
| SCHEMBL23960202 | 0.72 | EIF4A3 (0.41) | FABP3FABP4TRPA1PTGS1CACNA1C | |
| SCHEMBL2381701 | 0.72 | ALDH1A1 (0.43) | CYP3A4HPGDKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021020429-A1 | UREA COMPOUND FOR ANTAGONIZING LPA1 RECEPTOR | 大正製薬株式会社 | 2021-02-04 | — | — | WO | disclosed |