Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 5/20 | 0.42 |
| ▸ | GRM8 | O00222 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5161949 | 0.87 | HRH1 (0.67) | CYP19A1SLC6A2SLC6A4SLC6A3KCNK2 | |
| SCHEMBL4618800 | 0.87 | HRH1 (0.62) | CYP19A1HRH1TAAR1 | |
| Hydrochloric Acid SCHEMBL4433367 | 0.86 | HRH1 (0.64) | CYP19A1SLC6A2SLC6A4SLC6A3KCNK2 | |
| Hydrochloric Acid SCHEMBL9662256 | 0.85 | HRH1 (0.60) | CYP19A1HRH1TAAR1MAOB | |
| SCHEMBL4432789 | 0.84 | SLC6A2 (0.48) | CYP19A1SLC6A2SLC6A4SLC6A3KCNK2 | |
| Hydrochloric Acid SCHEMBL4430219 | 0.83 | SLC6A2 (0.47) | CYP19A1SLC6A2SLC6A4SLC6A3KCNK2 | |
| SCHEMBL23960431 | 0.82 | CYP19A1 (0.54) | CYP19A1GRM8GRM4TACR1PAX8 | |
| SCHEMBL7279759 | 0.81 | HRH1 (0.75) | CYP19A1SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL4433142 | 0.80 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3KCNK2KCNH2 | |
| SCHEMBL4617053 | 0.80 | HRH1 (0.50) | CYP19A1SLC6A2SLC6A4SLC6A3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214048-A1 | DUAL INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE AND 5-LIPOXYGENASE | Johann Wolfgang Goethe-Universität Frankfurt am Main (DE) | 2021-10-28 | — | — | WO | disclosed |