SCHEMBL23960848

SCHEMBL23960848

Cc1cc(C(C)(C)C)ccc1-c1ccncc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 4/20 0.59
GCGR P47871 1/20 0.46
RORC P51449 2/20 0.43
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
HPGD P15428 2/20 0.42
LMNA P02545 2/20 0.42
MAPT P10636 2/20 0.42
TSHR P16473 2/20 0.42
TP53 P04637 1/20 0.42
HTT P42858 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
PDE3B Q13370 2/20 0.41
PDE3A Q14432 2/20 0.41
S1PR1 P21453 1/20 0.41
S1PR3 Q99500 1/20 0.41
PPARG P37231 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
ALDH1A1 P00352 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13762184 0.79 DGAT1 (0.44) KIF11NPC1RAB9AHPGDTSHR
SCHEMBL8467570 0.79 ALDH1A1 (0.50) KIF11NPC1RAB9AHPGDLMNA
SCHEMBL13393498 0.78 NPC1 (0.60) GCGRNPC1RAB9ALMNAMAPT
SCHEMBL23960856 0.78 PARP10 (0.44) KIF11RORCNPC1RAB9AS1PR1
SCHEMBL21627244 0.77 PDE3B (0.55) GCGRNPC1RAB9AHPGDLMNA
SCHEMBL12165254 0.77 NPC1 (0.51) KIF11NPC1RAB9AHPGDLMNA
SCHEMBL23960825 0.76 KIF11 (0.57) KIF11GCGRNPC1RAB9AHPGD
SCHEMBL15317753 0.76 KIF11 (0.57) KIF11GCGRNPC1RAB9AHPGD
SCHEMBL18174620 0.75 KIF11 (0.49) KIF11GCGRNPC1RAB9AHPGD
SCHEMBL3999289 0.74 KIF11 (1.00) KIF11GCGRNPC1RAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210332290-A1 ORGANIC LIGHT-EMITTING MATERIAL BASED ON A PLATINUM TETRADENTATE ONCN COMPLEX, PREPARATION METHOD AND APPLICATION THEREOF IN ORGANIC LIGHT-EMITTING DIODES GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD (CN) 2021-10-28 US disclosed