SCHEMBL23964171

SCHEMBL23964171

c1ccc2[nH]c(CN3CCN(c4ccncc4)CC3)nc2c1

nearest known ligand 0.82

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DRD4 P21917 16/20 0.82
NPC1 O15118 1/20 0.75
GAA P10253 1/20 0.75
DRD2 P14416 2/20 0.67
HTR1A P08908 1/20 0.67
ADRA2C P18825 1/20 0.67
HTR2A P28223 1/20 0.67
KDM4E B2RXH2 1/20 0.66
ALDH1A1 P00352 1/20 0.66
CYP3A4 P08684 1/20 0.66
ALOX15 P16050 1/20 0.66
OPRK1 P41145 1/20 0.66
SIGMAR1 Q99720 1/20 0.66
HPGD P15428 1/20 0.65
HTT P42858 1/20 0.64
GRM2 Q14416 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4809921 0.91 DRD4 (1.00) DRD4NPC1GAADRD2HTR1A
SCHEMBL5157052 0.86 HTT (0.84) DRD4NPC1GAADRD2HTR1A
SCHEMBL8687797 0.86 DRD4 (1.00) DRD4NPC1GAADRD2HTR1A
SCHEMBL6787298 0.86 DRD4 (1.00) DRD4NPC1GAADRD2HTR1A
SCHEMBL4814328 0.86 NPC1 (1.00) DRD4NPC1GAADRD2HTR1A
SCHEMBL4809160 0.83 DRD4 (1.00) DRD4NPC1GAADRD2KDM4E
SCHEMBL3400090 0.83 DRD4 (0.77) DRD4GAAHTR1AKDM4EALDH1A1
SCHEMBL8689422 0.83 DRD4 (1.00) DRD4NPC1GAADRD2HTR1A
SCHEMBL383213 0.82 DRD4 (0.77) DRD4NPC1GAADRD2HTR1A
SCHEMBL31267420 0.81 DRD4 (0.72) DRD4NPC1GAADRD2HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775261-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2025-04-08 CN disclosed
CN-115427404-B Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2024-12-13 CN disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
EP-4139291-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF Anima Biotech Inc. (US) 2023-03-01 EP disclosed
CN-115427404-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2022-12-02 CN disclosed
WO-2021216665-A9 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-12-02 WO disclosed
WO-2021216665-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF COL1A1, COL2A1, COL14A1 DRD4 4746/4885NPC1 3136/4885GAA 1678/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.