SCHEMBL23964197

SCHEMBL23964197

c1ccc2oc(CN3CCN(c4c[nH]nn4)CC3)nc2c1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DRD3 P35462 6/20 0.47
DRD2 P14416 4/20 0.47
DRD4 P21917 2/20 0.47
DRD1 P21728 2/20 0.44
PIK3CD O00329 1/20 0.43
PIK3CB P42338 1/20 0.43
NPC1 O15118 1/20 0.42
MAPT P10636 1/20 0.42
RAB9A P51151 1/20 0.42
SOS1 Q07889 1/20 0.41
KCNH2 Q12809 1/20 0.40
LMNA P02545 1/20 0.40
TP53 P04637 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23964209 0.78 DRD3 (0.49) DRD3DRD2DRD4DRD1PIK3CD
SCHEMBL23964351 0.76 DRD4 (0.49) DRD3DRD2DRD4DRD1NPC1
SCHEMBL23964258 0.76 DRD3 (0.50) DRD3DRD2DRD4DRD1PIK3CD
SCHEMBL23964128 0.76 DRD3 (0.45) DRD3DRD2DRD4DRD1PIK3CD
SCHEMBL23964165 0.75 DRD3 (0.49) DRD3DRD2DRD4DRD1PIK3CD
SCHEMBL4908136 0.75 SOS1 (0.67) DRD3DRD2DRD4NPC1MAPT
SCHEMBL1514939 0.75 SOS1 (0.67) DRD3DRD2DRD4NPC1MAPT
SCHEMBL23964195 0.75 DRD3 (0.60) DRD3DRD2DRD4DRD1NPC1
SCHEMBL23964199 0.75 DRD3 (0.44) DRD3DRD2DRD4DRD1PIK3CD
SCHEMBL10566155 0.74 DRD3 (0.60) DRD3DRD2DRD4DRD1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
WO-2021216665-A9 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-12-02 WO disclosed
WO-2021216665-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF COL1A1, COL2A1, COL14A1 DRD3 4747/4885DRD2 4780/4885DRD4 4746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.