SCHEMBL23964351

SCHEMBL23964351

c1ccc2oc(CN3CCN(c4ccncn4)CC3)nc2c1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DRD4 P21917 5/20 0.49
DRD3 P35462 6/20 0.47
DRD2 P14416 5/20 0.47
SORD Q00796 3/20 0.47
DRD1 P21728 2/20 0.44
NPC1 O15118 1/20 0.42
MAPT P10636 1/20 0.42
RAB9A P51151 1/20 0.42
KCNH2 Q12809 1/20 0.42
PARP1 P09874 1/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP3A4 P08684 1/20 0.41
ALOX15 P16050 1/20 0.41
OPRK1 P41145 1/20 0.41
SIGMAR1 Q99720 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL30041168 0.94 SORD (0.45) DRD4DRD3DRD2SORDDRD1
SCHEMBL23964195 0.83 DRD3 (0.60) DRD4DRD3DRD2DRD1NPC1
SCHEMBL23964132 0.78 DRD3 (0.45) DRD4DRD3DRD2DRD1NPC1
SCHEMBL23932587 0.78 DRD3 (0.48) DRD4DRD3DRD2DRD1NPC1
SCHEMBL23964165 0.78 DRD3 (0.49) DRD4DRD3DRD2SORDDRD1
Formic Acid SCHEMBL23932580 0.77 DRD3 (0.54) DRD4DRD3DRD2DRD1NPC1
SCHEMBL23964258 0.76 DRD3 (0.50) DRD4DRD3DRD2DRD1NPC1
SCHEMBL23964197 0.76 DRD3 (0.47) DRD4DRD3DRD2DRD1NPC1
SCHEMBL23932551 0.76 HSD11B1 (0.44) DRD4DRD3DRD2DRD1KCNH2
SCHEMBL28962374 0.76 DRD4 (0.45) DRD4DRD3DRD2DRD1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
CN-115427404-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2022-12-02 CN disclosed
WO-2021216665-A9 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-12-02 WO disclosed
WO-2021216665-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF COL1A1, COL2A1, COL14A1 DRD4 4746/4885DRD3 4747/4885DRD2 4780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.