SCHEMBL23964233

SCHEMBL23964233

c1cc(N2CCN(Cc3ccc4[nH]ccc4c3)CC2)ccn1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.50
CYP17A1 P05093 1/20 0.48
CYP11B1 P15538 1/20 0.48
CYP11B2 P19099 1/20 0.48
HTR1A P08908 2/20 0.45
HTR1D P28221 1/20 0.45
HTR1B P28222 1/20 0.45
MAPK14 Q16539 3/20 0.45
POLB P06746 1/20 0.44
PARP1 P09874 1/20 0.44
TNK2 Q07912 1/20 0.44
TNK1 Q13470 1/20 0.44
ROCK2 O75116 2/20 0.44
CHRM4 P08173 1/20 0.43
CASP1 P29466 1/20 0.42
CASP4 P49662 1/20 0.42
CASP5 P51878 1/20 0.42
SLC2A1 P11166 1/20 0.42
DRD4 P21917 3/20 0.42
SIGMAR1 Q99720 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23932588 0.91 PARP1 (0.52) FAAHMAPK14POLBPARP1TNK2
SCHEMBL30040708 0.91 PARP1 (0.52) FAAHMAPK14POLBPARP1TNK2
SCHEMBL5755075 0.87 FAAH (0.61) FAAHHTR1AHTR1DHTR1BMAPK14
SCHEMBL5751064 0.87 FAAH (0.54) FAAHHTR1AHTR1DHTR1BMAPK14
SCHEMBL5754611 0.85 MAPT (0.57) FAAHHTR1AMAPK14DRD4SIGMAR1
SCHEMBL5755800 0.85 DRD4 (0.55) FAAHHTR1AHTR1DHTR1BMAPK14
SCHEMBL5750521 0.85 FAAH (0.50) FAAHHTR1AHTR1DHTR1BMAPK14
SCHEMBL5754613 0.85 FAAH (0.50) FAAHHTR1AHTR1DHTR1BMAPK14
SCHEMBL5753042 0.85 MAPT (0.57) FAAHHTR1AHTR1DHTR1BPOLB
SCHEMBL5751758 0.85 DRD4 (0.56) FAAHHTR1AHTR1DHTR1BMAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775261-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2025-04-08 CN disclosed
CN-115427404-B Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2024-12-13 CN disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
CN-115427404-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2022-12-02 CN disclosed
WO-2021216665-A9 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-12-02 WO disclosed
WO-2021216665-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF COL1A1, COL2A1, COL14A1 FAAH 3634/4885CYP17A1 3626/4885CYP11B1 1612/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.