Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 10/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25510443 | 0.83 | CYP2A6 (0.53) | METAP2KIF11SCN10ANPBWR1MAPT | |
| SCHEMBL8146720 | 0.77 | DAO (0.47) | — | |
| SCHEMBL28850023 | 0.76 | NPBWR1 (0.43) | METAP2KIF11NPBWR1DGAT1KCNH2 | |
| SCHEMBL17907971 | 0.75 | PDE5A (0.52) | METAP2KIF11 | |
| SCHEMBL17907969 | 0.75 | PDE5A (0.52) | METAP2KIF11 | |
| SCHEMBL28528849 | 0.73 | METAP2 (0.49) | METAP2KIF11SCN10ANPBWR1MAPT | |
| SCHEMBL2972649 | 0.73 | MAPT (0.60) | METAP2KIF11SCN10ANPBWR1MAPT | |
| SCHEMBL27278147 | 0.73 | METAP2 (0.49) | METAP2KIF11SCN10ANPBWR1MAPT | |
| SCHEMBL24354848 | 0.73 | GRIN2D (0.53) | MAPTHSD17B10CA12CA9 | |
| SCHEMBL31122113 | 0.73 | METAP2 (0.49) | METAP2KIF11SCN10ANPBWR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021216665-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | ANIMA BIOTECH INC. (US) | 2021-10-28 | — | — | WO | disclosed |