Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.49 |
| ▸ | KIF11 | P52732 | 10/20 | 0.45 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31122113 | 0.77 | METAP2 (0.49) | METAP2KIF11NPBWR1SCN10AMAPT | |
| SCHEMBL2972649 | 0.77 | MAPT (0.60) | METAP2KIF11NPBWR1SCN10AMAPT | |
| SCHEMBL27278147 | 0.77 | METAP2 (0.49) | METAP2KIF11NPBWR1SCN10AMAPT | |
| SCHEMBL20338421 | 0.74 | DAO (0.52) | METAP2 | |
| SCHEMBL30946289 | 0.73 | KIF11 (0.63) | METAP2KIF11MAPTDGAT1KCNH2 | |
| SCHEMBL20660889 | 0.73 | KIF11 (0.63) | METAP2KIF11MAPTDGAT1KCNH2 | |
| SCHEMBL23932536 | 0.73 | METAP2 (0.45) | METAP2KIF11NPBWR1SCN10AMAPT | |
| SCHEMBL24380299 | 0.73 | KIF11 (0.45) | METAP2KIF11NPBWR1SCN10AMAPT | |
| SCHEMBL22996064 | 0.73 | SCN10A (0.47) | METAP2KIF11NPBWR1SCN10AMAPT | |
| SCHEMBL23964236 | 0.73 | METAP2 (0.45) | METAP2KIF11NPBWR1SCN10AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112251771-B | Method for synthesizing C-2 bromo-indole by using electrochemical microchannel device | 南京先进生物材料与过程装备研究院有限公司 | 2021-12-03 | — | — | CN | disclosed |
| CN-112251771-A | Method for synthesizing C-2 bromo-indole by using electrochemical microchannel device | 南京先进生物材料与过程装备研究院有限公司 | 2021-01-22 | — | — | CN | disclosed |