SCHEMBL23964312

SCHEMBL23964312

Cn1cc(N2CCN(Cc3nc4ccc(F)cc4o3)CC2)nn1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.44
PIK3CB P42338 1/20 0.44
KCNH2 Q12809 2/20 0.43
CACNA1G O43497 1/20 0.43
SOS1 Q07889 1/20 0.42
LMNA P02545 2/20 0.42
TP53 P04637 3/20 0.40
MAPT P10636 3/20 0.38
MCHR1 Q99705 1/20 0.38
DRD4 P21917 1/20 0.37
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23964209 0.84 DRD3 (0.49) PIK3CDPIK3CBKCNH2LMNATP53
SCHEMBL25510914 0.79 LMNA (0.47) PIK3CDPIK3CBKCNH2CACNA1GSOS1
SCHEMBL30041055 0.74 HTT (0.47) PIK3CDPIK3CBKCNH2CACNA1GSOS1
SCHEMBL23932567 0.74 HTT (0.47) PIK3CDPIK3CBKCNH2CACNA1GSOS1
SCHEMBL23964198 0.73 DRD3 (0.53) KCNH2DRD4
SCHEMBL30040889 0.72 HTT (0.45) PIK3CDPIK3CBKCNH2CACNA1GSOS1
SCHEMBL30297599 0.72 HTT (0.45) PIK3CDPIK3CBKCNH2CACNA1GSOS1
SCHEMBL23932557 0.72 HTT (0.45) PIK3CDPIK3CBKCNH2CACNA1GSOS1
SCHEMBL23932516 0.72 HTT (0.45) PIK3CDPIK3CBKCNH2CACNA1GSOS1
SCHEMBL23964128 0.72 DRD3 (0.45) PIK3CDPIK3CBKCNH2MAPTDRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
WO-2021216665-A9 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-12-02 WO disclosed
WO-2021216665-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF COL1A1, COL2A1, COL14A1 PIK3CD 3553/4885PIK3CB 3338/4885KCNH2 4815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.