Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 4/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PTPRA | P18433 | 1/20 | 0.32 |
| ▸ | PTPRB | P23467 | 1/20 | 0.32 |
| ▸ | PTPRE | P23469 | 1/20 | 0.32 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23888018 | 0.82 | PTK2 (0.33) | IDO1RAPGEF4PTK2GAA | |
| SCHEMBL20375230 | 0.79 | IDO1 (0.41) | IDO1MAP2K1RAPGEF4PTK2PTPRC | |
| SCHEMBL20375142 | 0.79 | IDO1 (0.41) | IDO1MAP2K1RAPGEF4PTK2PTPRC | |
| SCHEMBL6561965 | 0.77 | IDO1 (0.40) | IDO1MAP2K1RAPGEF4PTK2PTPRC | |
| SCHEMBL10564036 | 0.76 | RAPGEF4 (0.56) | RAPGEF4GAAMEN1KMT2ATDP1 | |
| SCHEMBL18618504 | 0.74 | IDO1 (0.38) | IDO1MAP2K1RAPGEF4PTK2PTPRC | |
| SCHEMBL18618506 | 0.74 | IDO1 (0.38) | IDO1MAP2K1RAPGEF4PTK2PTPRC | |
| SCHEMBL13783444 | 0.74 | CYP3A4 (0.46) | IDO1MAP2K1PTPRCPTPN2PTPN1 | |
| SCHEMBL8064140 | 0.73 | ALDH1A1 (0.44) | MEN1KMT2ATDP1 | |
| SCHEMBL3219456 | 0.72 | IDO1 (0.50) | IDO1PTPRCPTPN2PTPN1PTPRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021213518-A1 | COMPOUND FOR PREVENTING OR TREATING LIPID METABOLISM-RELATED DISEASES | 复旦大学 (CN) | 2021-10-28 | — | — | WO | disclosed |