Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL709622 | 1.00 | TSHR (0.47) | TSHRMAPK1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL711057 | 0.93 | TSHR (0.44) | TSHRMAPK1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL711178 | 0.93 | TSHR (0.44) | TSHRMAPK1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL810670 | 0.93 | TSHR (0.44) | TSHRMAPK1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL19676889 | 0.89 | TSHR (0.49) | TSHRMAPK1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL8423671 | 0.85 | TSHR (0.43) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL16808766 | 0.85 | TSHR (0.57) | TSHRMAPK1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL16517868 | 0.85 | TSHR (0.57) | TSHRMAPK1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL8426911 | 0.84 | TSHR (0.42) | TSHRMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1412793 | 0.83 | TSHR (0.55) | TSHRMAPK1SMN1; SMN2HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214037-A1 | FLOW CELLS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2021-10-28 | — | — | WO | disclosed |