SCHEMBL711178

SCHEMBL711178

FC(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)COCC1CO1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
MAPK1 P28482 1/20 0.44
MAPT P10636 2/20 0.36
USP2 O75604 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
RECQL P46063 1/20 0.35
ALDH1A1 P00352 4/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
LMNA P02545 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
HPGD P15428 1/20 0.33
XBP1 P17861 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MEN1 O00255 1/20 0.31
TP53 P04637 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL810670 1.00 TSHR (0.44) TSHRMAPK1MAPTUSP2CYP1A2
SCHEMBL711057 1.00 TSHR (0.44) TSHRMAPK1MAPTUSP2CYP1A2
SCHEMBL23964677 0.93 TSHR (0.47) TSHRMAPK1MAPTCYP1A2CYP2C19
SCHEMBL709622 0.93 TSHR (0.47) TSHRMAPK1MAPTCYP1A2CYP2C19
SCHEMBL1412793 0.88 TSHR (0.55) TSHRMAPK1MAPTCYP1A2ALDH1A1
SCHEMBL19676889 0.86 TSHR (0.49) TSHRMAPK1ALDH1A1SMN1; SMN2LMNA
SCHEMBL16517868 0.86 TSHR (0.57) TSHRMAPK1MAPTCYP1A2ALDH1A1
SCHEMBL28362812 0.83 TSHR (0.39) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL28359120 0.83 TSHR (0.39) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL3901860 0.83 TSHR (0.50) TSHRMAPK1ALDH1A1SMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7038062-B2 Synthesis of cyclic trithiocarbonates from epoxides THE GOODYEAR TIRE & RUBBER COMPANY (US) 2006-05-02 US claimed
US-20060004210-A1 SYNTHESIS OF CYCLIC TRITHIOCARBONATES FROM EPOXIDES GOODYEAR TIRE & RUBBER COMPANY, THE 2006-01-05 US claimed
US-11710854-B2 Functional epoxides in catalyst-based electrolyte compositions for Li-ion batteries ENEVATE CORPORATION (US) 2023-07-25 US disclosed
US-11710854-B2 Functional epoxides in catalyst-based electrolyte compositions for Li-ion batteries ENEVATE CORPORATION (US) 2023-07-25 US disclosed
US-20220140392-A1 FUNCTIONAL EPOXIDES IN CATALYST-BASED ELECTROLYTE COMPOSITIONS FOR LI-ION BATTERIES ENEVATE CORPORATION 2022-05-05 US disclosed
US-11156750-B2 Laminated diffractive optical element and method for manufacturing laminated diffractive optical element CANON KABUSHIKI KAISHA (JP) 2021-10-26 US disclosed
US-20210223437-A1 OPTICAL ELEMENT AND METHOD FOR MANUFACTURING THE SAME CANON KK (JP) 2021-07-22 US disclosed
US-20210206998-A1 LIQUID REPELLENT DAIKIN INDUSTRIES, LTD. (JP) 2021-07-08 US disclosed
US-10996375-B2 Optical element and method for manufacturing the same CANON KABUSHIKI KAISHA (JP) 2021-05-04 US disclosed
EP-3385760-B1 OPTICAL ELEMENT AND METHOD FOR MANUFACTURING THE SAME CANON KK (JP) 2020-11-11 EP disclosed
US-10175576-B2 Curable composition for photo imprints, method for forming pattern, fine pattern, and method for manufacturing semiconductor device FUJIFILM CORPORATION (JP) 2019-01-08 US disclosed
WO-2005070988-A1 POLYMER FOR USE IN CONDUITS, MEDICAL DEVICES AND BIOMEDICAL SURFACE MODIFICATION UCL BIOMEDICA PLC (GB) 2005-08-04 WO disclosed
US-20050113246-A1 Process of producing an organic catalyst THE PROCTER & GAMBLE COMPANY 2005-05-26 US disclosed
WO-2005047264-A1 PROCESS FOR PRODUCING DIHYDROISOQUINOLINE ZWITTERIONS THE PROCTER & GAMBLE COMPANY (US) 2005-05-26 WO disclosed
US-6087072-A Article having a light-controllable super-water-repellent surface and a printing machine using the article HITACHI, LTD. (JP) 2000-07-11 US disclosed
US-6027852-A Article having a light-controllable super-water-repellent surface and a printing machine using the article HITACHI, LTD. (JP) 2000-02-22 US disclosed
US-5744678-A NICKEL COMPOUND, ORGANOPHOSPHORUS COMPOUND, ORGANOALUMINUM COMPOUND, CARBON-HALOGEN COMPOUNDS; CATALYST SELECTIVITY NIPPON OIL CO., LTD. (JP) 1998-04-28 US disclosed
EP-0758563-A1 OLEFIN OLIGOMERIZATION CATALYST AND PROCESS FOR THE PREPARATION OF OLEFIN OLIGOMER USING IT NIPPON OIL COMPANY, LTD. (JP) 1997-02-19 EP disclosed
US-5556821-A Catalyst component for the polymerization of olefins NIPPON OIL COMPANY, LIMITED (JP) 1996-09-17 US disclosed
EP-0587440-A2 Catalyst component for the polymerisation of olefins and process for preparing olefin polymers using same NIPPON OIL COMPANY, LIMITED (JP) 1994-03-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060004210-A1 SYNTHESIS OF CYCLIC TRITHIOCARBONATES FROM EPOXIDES TST, CXCR6, CCR6 TSHR 925/4885MAPK1 1824/4885MAPT 4769/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.