Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8426911 | 0.92 | TSHR (0.42) | TSHRMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL709622 | 0.85 | TSHR (0.47) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL23964677 | 0.85 | TSHR (0.47) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL1071670 | 0.81 | TSHR (0.53) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL16517868 | 0.81 | TSHR (0.57) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL16808766 | 0.81 | TSHR (0.57) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL9513868 | 0.80 | TSHR (0.52) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL1412793 | 0.79 | TSHR (0.55) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL711178 | 0.79 | TSHR (0.44) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL711057 | 0.79 | TSHR (0.44) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710211-A | REACTION OF POLYMER WITH COMPOUND HAVING A THIOL OR THIOESTER AND HYDROLYSIS TO FORM VINYL ALCOHOL | KURARAY CO., LTD. (JP) | 1998-01-20 | — | — | US | claimed |
| EP-0757060-B1 | Process for producing vinyl alcohol polymer | KURARAY CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| EP-0757060-A2 | Process for producing vinyl alcohol polymer | KURARAY CO., LTD. (JP) | 1997-02-05 | — | — | EP | disclosed |