Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL810670 | 1.00 | TSHR (0.44) | TSHRMAPK1MAPTUSP2CYP1A2 | |
| SCHEMBL711178 | 1.00 | TSHR (0.44) | TSHRMAPK1MAPTUSP2CYP1A2 | |
| SCHEMBL23964677 | 0.93 | TSHR (0.47) | TSHRMAPK1MAPTCYP1A2CYP2C19 | |
| SCHEMBL709622 | 0.93 | TSHR (0.47) | TSHRMAPK1MAPTCYP1A2CYP2C19 | |
| SCHEMBL1412793 | 0.88 | TSHR (0.55) | TSHRMAPK1MAPTCYP1A2ALDH1A1 | |
| SCHEMBL19676889 | 0.86 | TSHR (0.49) | TSHRMAPK1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL16517868 | 0.86 | TSHR (0.57) | TSHRMAPK1MAPTCYP1A2ALDH1A1 | |
| SCHEMBL28362812 | 0.83 | TSHR (0.39) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL28359120 | 0.83 | TSHR (0.39) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL3901860 | 0.83 | TSHR (0.50) | TSHRMAPK1ALDH1A1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7038062-B2 | Synthesis of cyclic trithiocarbonates from epoxides | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2006-05-02 | — | — | US | claimed |
| US-20060004210-A1 | SYNTHESIS OF CYCLIC TRITHIOCARBONATES FROM EPOXIDES | GOODYEAR TIRE & RUBBER COMPANY, THE | 2006-01-05 | — | — | US | claimed |
| US-11306109-B2 | Method for preparing silicon-containing heterocycles | HENKEL AG & CO. KGAA (DE) | 2022-04-19 | — | — | US | disclosed |
| US-11156750-B2 | Laminated diffractive optical element and method for manufacturing laminated diffractive optical element | CANON KABUSHIKI KAISHA (JP) | 2021-10-26 | — | — | US | disclosed |
| US-20210223437-A1 | OPTICAL ELEMENT AND METHOD FOR MANUFACTURING THE SAME | CANON KK (JP) | 2021-07-22 | — | — | US | disclosed |
| EP-3655452-B1 | SILYLATED POLYURETHANES AND METHODS FOR PREPARING THEREOF | HENKEL AG & CO KGAA (DE) | 2021-07-07 | — | — | EP | disclosed |
| US-10996375-B2 | Optical element and method for manufacturing the same | CANON KABUSHIKI KAISHA (JP) | 2021-05-04 | — | — | US | disclosed |
| US-10889682-B2 | Silylated polyurethanes and methods for preparing thereof | HENKEL AG & CO. KGAA (DE) | 2021-01-12 | — | — | US | disclosed |
| EP-3385760-B1 | OPTICAL ELEMENT AND METHOD FOR MANUFACTURING THE SAME | CANON KK (JP) | 2020-11-11 | — | — | EP | disclosed |
| EP-3655452-A1 | SILYLATED POLYURETHANES AND METHODS FOR PREPARING THEREOF | Henkel AG & Co. KGaA (DE) | 2020-05-27 | — | — | EP | disclosed |
| EP-3655411-A1 | METHOD FOR PREPARING SILICON-CONTAINING HETEROCYCLES | Henkel AG & Co. KGaA (DE) | 2020-05-27 | — | — | EP | disclosed |
| EP-1057845-B1 | PROCESS FOR PRODUCING POLYETHER | KAO CORP (JP) | 2004-01-21 | — | — | EP | disclosed |
| US-20030087163-A1 | Volume type hologram recording photosensitive composition, volume type hologram recording medium using the same and method of producing volume type hologram | DAI NIPPON PRINTING CO., LTD. (JP) | 2003-05-08 | — | — | US | disclosed |
| US-6417323-B1 | RING-OPENING POLYMERIZATION OF SUBSTITUTED EPOXIDE IN RARE EARTH COMPOUND AND REDUCING AGENT PRESENCE; ETHERIFICATION | KAO CORPORATION (JP) | 2002-07-09 | — | — | US | disclosed |
| EP-1057845-A1 | PROCESS FOR PRODUCING POLYETHER | Kao Corporation (JP) | 2000-12-06 | — | — | EP | disclosed |
| US-5744678-A | NICKEL COMPOUND, ORGANOPHOSPHORUS COMPOUND, ORGANOALUMINUM COMPOUND, CARBON-HALOGEN COMPOUNDS; CATALYST SELECTIVITY | NIPPON OIL CO., LTD. (JP) | 1998-04-28 | — | — | US | disclosed |
| EP-0758563-A1 | OLEFIN OLIGOMERIZATION CATALYST AND PROCESS FOR THE PREPARATION OF OLEFIN OLIGOMER USING IT | NIPPON OIL COMPANY, LTD. (JP) | 1997-02-19 | — | — | EP | disclosed |
| US-5556821-A | Catalyst component for the polymerization of olefins | NIPPON OIL COMPANY, LIMITED (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0587440-A2 | Catalyst component for the polymerisation of olefins and process for preparing olefin polymers using same | NIPPON OIL COMPANY, LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |
| EP-0147758-A2 | Polyesters modified with polymers of alkylene oxids | The B.F. GOODRICH Company (US) | 1985-07-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004210-A1 | SYNTHESIS OF CYCLIC TRITHIOCARBONATES FROM EPOXIDES | TST, CXCR6, CCR6 | TSHR 925/4885MAPK1 1824/4885MAPT 4769/4885 |
| US-11306109-B2 | Method for preparing silicon-containing heterocycles | C1S, C1R, C5 | TSHR 1663/4885MAPK1 1757/4885MAPT 4861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.