Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22213296 | 0.64 | KMT2A (0.54) | MKNK1KDM4EMEN1ALDH1A1GAA | |
| SCHEMBL23964749 | 0.59 | KDM4E (0.36) | MKNK1KDM4EMEN1ALDH1A1GLA | |
| SCHEMBL23964783 | 0.57 | MEN1 (0.50) | KDM4EMEN1ALDH1A1GLAGAA | |
| SCHEMBL14922277 | 0.52 | ALDH1A1 (0.67) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL18035002 | 0.51 | MCHR1 (0.55) | — | |
| SCHEMBL4142914 | 0.51 | DRD2 (0.45) | MEN1ALDH1A1GAAMAPTKMT2A | |
| SCHEMBL11005182 | 0.50 | KMT2A (0.41) | KDM4EMEN1ALDH1A1GLAGAA | |
| SCHEMBL12489583 | 0.50 | OGA (0.51) | KMT2A | |
| SCHEMBL10515481 | 0.50 | KDM4E (0.47) | KDM4EMEN1ALDH1A1GLAGAA | |
| SCHEMBL16624342 | 0.49 | CHRM2 (0.59) | MEN1ALDH1A1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3680243-B1 | PENTACYCLIC COMPOUND | EISAI R&D MAN CO LTD (JP) | 2021-10-27 | — | — | EP | disclosed |