SCHEMBL23964820

SCHEMBL23964820

Cc1cc(-c2ccc(C(C)C)c(C)c2)ccc1C(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
CYP3A4 P08684 1/20 0.44
TSHR P16473 1/20 0.44
LMNA P02545 3/20 0.43
HPGD P15428 1/20 0.43
TRPA1 O75762 1/20 0.43
CHRM1 P11229 1/20 0.43
SLC6A2 P23975 1/20 0.43
ADRA1A P35348 1/20 0.43
HTR2B P41595 1/20 0.43
KDM4E B2RXH2 2/20 0.39
CARM1 Q86X55 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
GPR55 Q9Y2T6 1/20 0.37
PLA2G1B P04054 1/20 0.37
ATG4B Q9Y4P1 1/20 0.37
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14570075 0.87 NAAA (0.39) ALDH1A1TDP1CYP3A4TSHRLMNA
SCHEMBL28083234 0.87 ESR1 (0.45) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL10304809 0.87 TNKS2 (0.41) ALDH1A1TDP1CYP3A4TSHRLMNA
SCHEMBL22327698 0.85 ALDH1A1 (0.36) ALDH1A1TDP1CYP3A4TSHRLMNA
SCHEMBL13385257 0.85 PGR (0.37) ALDH1A1TDP1CYP3A4TSHRLMNA
SCHEMBL10304785 0.85 AKR1C3 (0.42) ALDH1A1TDP1CYP3A4TSHRLMNA
SCHEMBL13385400 0.84 ALDH1A1 (0.35) ALDH1A1TDP1CYP3A4TSHRLMNA
SCHEMBL10304845 0.84 MAPT (0.42) ALDH1A1CYP3A4TSHRLMNAHPGD
SCHEMBL13385181 0.84 DYRK1A (0.47) ALDH1A1CARM1MEN1KMT2A
SCHEMBL23457318 0.84 ALDH1A1 (0.38) ALDH1A1TDP1CYP3A4TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220017645-A1 CHARGE-BEARING CYCLODEXTRIN POLYMERIC MATERIALS AND METHODS OF MAKING AND USING SAME AVENUE GLOBAL DISLOCATION OPPORTUNITIES FUND, L.P. AND AVENUE GLOBAL OPPORTUNITIES MASTER FUND, L.P. 2022-01-20 US disclosed
US-11155646-B2 Charge-bearing cyclodextrin polymeric materials and methods of making and using same CYCLOPURE, INC. (US) 2021-10-26 US disclosed