Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GRM5 | P41594 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31480604 | 0.83 | KDM4E (0.62) | ALDH1A1GRM5SMN1; SMN2KDM4ELMNA | |
| SCHEMBL25487645 | 0.83 | KDM4E (0.62) | ALDH1A1GRM5SMN1; SMN2KDM4ELMNA | |
| SCHEMBL15652792 | 0.81 | ALDH1A1 (0.47) | ALDH1A1GRM5SMN1; SMN2KDM4ELMNA | |
| SCHEMBL18247131 | 0.81 | GRM5 (0.51) | ALDH1A1GRM5MAPTCYP1A2SMN1; SMN2 | |
| SCHEMBL29597769 | 0.81 | GRM5 (0.51) | ALDH1A1GRM5MAPTCYP1A2SMN1; SMN2 | |
| Potassium Ion SCHEMBL28087711 | 0.80 | ALDH1A1 (0.46) | ALDH1A1GRM5SMN1; SMN2GAARAB9A | |
| SCHEMBL69653 | 0.80 | MAPT (0.64) | ALDH1A1MAPTCYP1A2SMN1; SMN2GAA | |
| SCHEMBL16834540 | 0.80 | ALDH1A1 (0.49) | ALDH1A1GRM5MAPTCYP1A2SMN1; SMN2 | |
| SCHEMBL1620864 | 0.79 | GRM5 (0.50) | ALDH1A1GRM5MAPTCYP1A2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1620862 | 0.78 | GRM5 (0.49) | ALDH1A1GRM5MAPTCYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158025-A1 | GALACTOKINASE INHIBITORS | NATIONAL INSTITUTES OF HEALTH | 2023-05-25 | — | — | US | disclosed |
| WO-2021216812-A1 | GALACTOKINASE INHIBITORS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2021-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230158025-A1 | GALACTOKINASE INHIBITORS | GALK1, GCK, GCKR | ALDH1A1 3139/4885GRM5 1663/4885MAPT 2129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.